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The dose of intraperitoneal cisplatin used in this study has previously been given in combination with intravenous paclitaxel and with intravenous cyclophosphamide and in a phase 2 trial of the same regimen with acceptable toxicity.
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Many warts regress spontaneously (particularly common warts); others persist for years and recur at the same or different sites, even with treatment.
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The protocol of the study is based on the protocol for the study in Example 29, except that the order of the lesion-directed therapy and the field-directed therapy is reversed.
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Leibovitch et al had similar findings in their prospective case series study of 70 patients, which revealed an 8% recurrence rate within 5 years in patients treated with MMS, a rate lower than other non-MMS modalities.
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Grossman and Leffell 2 explain that UV radiation is involved in the pathogenesis of AKs through inducing cellular DNA mutations in the skin, which may affect cell proliferation genes, such as p53 and ras, or prompt evasion of apoptosis.
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Proposing clinical trials of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer peritoneal carcinomatosis.
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Application of dermatologic products such as sunscreens, cosmetics, and other drug products was not permitted.
Methods: A review identified 15 patients with biopsy-proven actinic cheilitis who had been treated with topical imiquimod 3 times weekly for 4 to 6 weeks.
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Stockfleth E, Kerl H; Guideline Subcommittee of the European Dermatology Forum.
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There was no statistical difference in the risk reduction associated with intraperitoneal therapy between the subgroup with gross visible residual disease and the subgroup with no visible residual disease at initial surgery ().
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By 1 year, the recurrence rates in the radiation and cryotherapy arms were 4% and 39%, respectively, in a per-protocol analysis.
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Efficacy of anti-death receptor 5 (DR5) antibody (TRA-8) against primary human ovarian carcinoma using a novel ex vivo tissue slice model.
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