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Serotonin reuptake inhibitors in pregnancy and the risk of major malformations: a systematic review".
Selegiline, when taken at a low dose of 6 milligrams per day, does not cause this problem, and can therefore be taken without having to restrict the diet.
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In the study where the half-life of MAO-B inhibition was measured in humans, it was about 38 days in the normal subjects and 43 days for patients with early Parkinson's disease.
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It was also proposed that in the rat brain selegiline could increase the level of -phenylethylamine, an endogenous trace amine which potentiates neuronal response to dopamine.
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